What causes prostate cancer?

March 8, 2024

The exact cause of prostate cancer is not fully understood, but it is believed to result from a combination of genetic, environmental, and lifestyle factors. Some factors that may contribute to the development of prostate cancer include:

  1. Age: Prostate cancer is more common in older men, with the risk increasing with age. It is rare in men under 40 but becomes more common with each decade of life thereafter.
  2. Family history: Men with a family history of prostate cancer, particularly in close relatives such as a father or brother, have an increased risk of developing the disease themselves. Certain genetic mutations may also play a role in inherited forms of prostate cancer.
  3. Race and ethnicity: Prostate cancer occurs more frequently in African American men than in men of other racial or ethnic groups. It is less common in Asian American and Hispanic/Latino men.
  4. Hormonal factors: Androgens, such as testosterone, play a role in the development and growth of prostate cancer. Men with higher levels of androgens or conditions that increase androgen levels may be at increased risk of developing prostate cancer.
  5. Lifestyle factors: Certain lifestyle factors may increase the risk of prostate cancer, including a diet high in red meat and dairy products, obesity, smoking, and lack of physical activity. However, the evidence linking these factors to prostate cancer risk is not definitive.
  6. Environmental exposures: Exposure to certain environmental toxins or chemicals may increase the risk of prostate cancer, although the specific agents involved are not well-defined.

It’s important to note that having one or more risk factors for prostate cancer does not mean that a man will definitely develop the disease. Many men with prostate cancer do not have any known risk factors, and not all men with risk factors will develop prostate cancer.

Regular medical check-ups, including discussions with healthcare providers about prostate cancer screening, can help detect the disease early when it is most treatable. Screening for prostate cancer typically involves a combination of a digital rectal examination (DRE) and a prostate-specific antigen (PSA) blood test. Treatment options for prostate cancer vary depending on the stage and aggressiveness of the cancer and may include active surveillance, surgery, radiation therapy, hormone therapy, chemotherapy, or other treatments.